NEI Audacious Goals Initiative…restoring vision through regeneration of the retina
The Audacious Goals Initiative (AGI) is an effort by the National Eye Institute to push the boundaries of vision science. By facilitating cross-disciplinary research, the AGI is tackling the most devastating and difficult-to-treat eye diseases.
News
New AGI workshop report: Creating a Cellular Environment for Neuroregeneration (April 6, 2018)
AGI Projects
Imaging Projects: Five bold projects will develop new technology to noninvasively image cells of the eye in unprecedented detail.
Discovery-based Projects: Six NEI Audacious Goals Initiative (AGI) projects aim to identify biological factors that affect neural regeneration in the retina.
AGI Events and Reports
NEI AGI is hosting a town hall meeting at the Association for Research in Vision and Ophthalmology annual meeting. ”Bringing regenerative medicine therapies to the clinic,” takes place Tuesday, May, 1, 2018, Ballroom A, Hawaii Convention Center, Honolulu.
About the Initiative
The NEI AGI is catalyzing research that will enable the restoration of vision through regeneration of the retina. The central goal is to replace cells of the retina that have been damaged by disease or injury and to restore their connections to the visual centers of the brain. Through strategic research funding, the NEI is enlisting dynamic scientists and teams who are developing the necessary knowledge and technology to make the goal a reality. Read more about the AGI.
About the Goal
The NEI audacious goal is to regenerate neurons and neural connections in the eye and visual system. The NEI AGI is targeting the photoreceptors and retinal ganglion cells. Photoreceptors—often called rods and cones—are cells in the retina that when stimulated by light generate signals the brain perceives as images. The retinal ganglion cells carry the signals from the photoreceptors to the brain. Read more about the audacious goal.
Funding Opportunities
Translation-Enabling Models to Evaluate Survival and Integration of Regenerated Neurons in the Visual System. (December 8, 2017)