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Wadih Zein, M.D.

Wadih Zein

National Eye Institute (NEI),
National Institutes of Health (NIH), Bethesda, MD

  • Staff Clinician, Ophthalmic Genetics and Visual Function Branch


  • Ophthalmology
  • Pediatric Ophthalmology
  • Adult Strabismus
  • Ophthalmic Genetics and Visual Function

Current Projects

Dr. Zein studies hereditary pediatric eye diseases affecting the retina including retinitis pigmentosa, Leber congenital amaurosis, Stargardt disease, and Best disease. Additionally, he investigates systemic hereditary diseases that can affect the eye such as Usher syndrome, Bardet-Biedl syndrome, Alstrom syndrome, Joubert syndrome, WAGR syndrome, and albinism. Dr. Zein's research focuses on the natural history and the pathobiology of these diseases in the hopes of gaining a greater understanding of these conditions. He also concentrates on the psychophysical and electrophysiological studies of ocular function. Dr. Zein has been the principal investigator of the NEI Usher syndrome protocol 05-EI-0096 since 2010.

Professional Highlights

Dr. Zein joined the NEI clinical staff in 2009 after completing fellowships at the NEI Ophthalmic Genetics and Visual Function Branch and Children's National Medical Center/The George Washington University in Washington, D.C. In 2003, he completed his residency in ophthalmology at the American University of Beirut in Lebanon. He serves as an ophthalmology advisor and member of the scientific board of multiple patient associations for hereditary disease with ocular manifestations.


Dr. Zein has authored and co-authored numerous scientific manuscripts and book chapters including publications in Ophthalmology, American Journal of Medical Genetics, Archives of Ophthalmology, Cortex, Human Mutations, International Ophthalmology, Journal of Medical Genetics, Eye, and Retina.

See the Spokesperson in Action

Interview with Wadih Zein, M.D.: Why Is Clinical Research Important?

Interview with Wadih Zein, M.D.: What Is Clinical Research?

The National Eye Institute (NEI), part of the National Institutes of Health, leads the federal government's research on the visual system and eye diseases. NEI supports basic and clinical science programs that result in the development of sight-saving treatments.

National Eye Institute
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