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Frederick L. Ferris III, M.D.

Frederick L. Ferris

National Eye Institute (NEI)
National Institutes of Health (NIH), Bethesda, MD.

  • Director, Division of Epidemiology and Clinical Applications (DECA)
  • Clinical Director


  • Retinal diseases
  • Age-related macular degeneration
  • Diabetic retinopathy
  • Clinical trials
  • Epidemiology
  • Nutrition and vision

Current Projects

Dr. Ferris is actively involved in the Diabetic Retinopathy Clinical Research Network (DRCR.net), through which researchers at clinics around the country collaborate to conduct research of diabetic eye disease. He is also involved in the Age-Related Eye Disease Study 2 (AREDS 2), which is evaluating supplements containing plant- and fish-derived nutrients for preventing advanced age-related macular degeneration.


Dr. Ferris is the author of more than 200 research articles in peer-reviewed journals, including American Journal of Ophthalmology, Archives of Ophthalmology, Journal of the American Medical Association, Lancet, and the New England Journal of Medicine.

Research Highlights

Dr. Ferris has analyzed, designed, and chaired several landmark clinical trials, including:

  • Early Treatment Diabetic Study (ETDRS), which demonstrated that laser treatment could reduce rates of severe vision loss by up to 95 percent in people with diabetic retinopathy.
  • Age Related Eye Disease Study (AREDS), which found that nutritional supplements with high levels of certain antioxidants and minerals significantly reduced the risk of vision loss for people with intermediate age-related macular degeneration.

The National Eye Institute (NEI), part of the National Institutes of Health, leads the federal government's research on the visual system and eye diseases. NEI supports basic and clinical science programs that result in the development of sight-saving treatments.

National Eye Institute
(301) 496-5248