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Posters Session

Reciprocal Modulations of Wnt Signaling Enhance Retinal Regeneration by Increasing Stem Cell Proliferation Rates and Promoting Cell-specific Differentiation
Junko Ariga and Jeff Mumm
Vision Discovery Institute, Cellular Biology & Anatomy Department, Georgia Health Sciences University
Email: jmumm@georgiahealth.edu

Histone Marks Predict Cell Plasticity of the Adult Human Retinal Pigment Epithelium
Timothy Adam Blenkinsop1, Alvaro Rada-Iglesias2, Joanna Wysocka2, Carol Charniga1, and Sally Temple1
1Neural Stem Cell Institute, Rensselaer, NY; 2Department of Chemical & Systems Biology, Stanford University School of Medicine
Email: tblenkinsop@gmail.com

Characterization of a RPE-Specific GFP Expressing iPS Cell Line for its Ability to Generate Authentic RPE
Janine Davis1, Kent Fang1, Qin Wan1, Helen May-Simera2, Barbara Corneo3, Sally Temple3, Heinz Arnheiter4, Sheldon Miller1, and Kapil Bharti1,4
1Section on Epithelial & Retinal Physiology & Disease, National Eye Institute, NIH; 2Retinal Cell Biology & Degeneration Section, Neurobiology-Neurodegeneration & Repair Laboratory, National Eye Institute, NIH; 3New York Neural Stem Cell Institute, Rensselaer, NY; 4Mammalian Development Section, National Institute for Neurological Disorders & Stroke, NIH
Email: kapilbharti@mail.nih.gov

Cell Therapy in a Swine Model of Retinitis Pigmentosa
Juan Fernandez de Castro1, Wei Wang1, Eric Vukmanic1, Douglas Emery1, Paul DeMarco1,2, Douglas Dean1, Maureen McCall1,2, Henry Kaplan1
1Departments of Ophthalmology & 2Psychological & Brain Sciences, University of Louisville
E-mail: jpfern01@louisville.edu

Complement Factor C3a is a Potent Inducer of Retina Regeneration
Tracy Haynes1, Apostolia Tzekou2, Agustin Luz Madrigal1, Nancy Paola Echeverri1, Erika Grajales-Esquivel1, Panagiotis A. Tsonis3, John D. Lambris2 and Katia Del Rio-Tsonis1
1Department of Zoology, Miami University; 2Department of Pathology & Laboratory Medicine, University of Pennsylvania; 3Department of Biology, University of Dayton
E-mail: haynest@muohio.edu

Control of Retinal Ganglion Cell Differentiation
Jonathan Hertz1, Xiaolu Jin1, Janet Li1, Kristina Russano1, Brooke DeRosa2, Derek Dyxhoorn2, Veronique Lefebvre3, and Jeffrey Goldberg1
1Bascom Palmer Eye Institute, Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine; 2John P. Hussman Institute for Human Genomics, Dr. John T. MacDonald Foundation Department of Human Genetics, University of Miami Miller School of Medicine; 3Department of Cell Biology, Orthopaedic & Rheumatologic Research Center, Cleveland Clinic Lerner Research Institute

Towards an iPSC Model of Glaucoma
Alex W. Hewitt1,2,3,4, Jamie E Craig5, Helena Liang1,2, Mirella Dottori1,2, Jonathan Crowston1,2,3, and David Mackey1,3,4
1Centre for Eye Research Australia; 2University of Melbourne, Australia; 3Royal Victorian Eye & Ear Hospital; 4Lions Eye Institute, University of Western Australia; 5Department of Ophthalmology, Flinders University, Flinders Medical Centre, Australia

Context Dependent Function of Math5 (Atoh7) in Retinal Ganglion Cell Genesis
Lev Prasov and Tom Glaser
Department of Human Genetics, University of Michigan
E-mail: lprasov@umich.edu

Comparisons of the Transcriptome and Tight junctions Between Human Fetal and Stem Cell-derived Retinal Pigment Epithelia
Lawrence J Rizzolo1, Shaomin Peng1, Geliang Gan1, and Caihong Qui2
1Departments of Surgery & Ophthalmology & Visual Science & 2Department of Cell Biology, Yale University
E-mail: larry.rizzolo@yale.edu

Directing Virus-free Human Induced Pluripotent Stem Cells to Differentiate into Retinal Cells
Xiufeng Zhong1, Christian Gutierrez1, Christopher Hampton1, Tea Soon Park2, David M. Gamm3, Elias Zambidis2, and Valeria Canto-Soler1
1Wilmer Eye Institute, Johns Hopkins University School of Medicine; 2Institute for Cell Engineering, Johns Hopkins University School of Medicine; 3Department of Ophthalmology & Visual Sciences, University of Wisconsin School of Medicine & Public Health
E-mail: xzhong13@jhmi.edu