During aging, loss of vision and cognition often coincide. In a new study, researchers funded by the National Eye Institute (NEI) and the National Institute on Aging (NIA) have found that vision loss precedes loss of mental capacity.
Vision researcher, T. Michael Redmond, Ph.D., chief of the National Eye Institute (NEI) Laboratory of Retinal Cell and Molecular Biology, is a recipient of the 2018 António Champalimaud Vision Award for foundational science discoveries about the molecular biology of the retina, the light-sensing tissue at the back of the eye. His work deduced how the RPE65 gene converts dietary vitamin A into a form of the vitamin that is central to the workings of the visual cycle, the enzymatic processes by which the eye converts light into electrical signals sent to the brain.
Scientists funded by the National Eye Institute (NEI) report a novel gene therapy that halts vision loss in a canine model of a blinding condition called autosomal dominant retinitis pigmentosa (adRP). The strategy could one day be used to slow or prevent vision loss in people with the disease.