Gyrate atrophy of the choroid and retina is the most common symptom of a rare congenital metabolic disorder called hyperornithinemia. People born with hyperornithinemia lack an enzyme needed to break down a protein, called ornithine, which accumulates in the body.
The ongoing loss of cells (atrophy) in the retina starts during childhood with myopia (nearsightedness) and night blindness, followed by loss of side vision (tunnel vision). At this time, there is no cure for this disease.
Currently, the NEI does not have a fact sheet on this condition.
For more information from other health sites, please visit the following webpages:
Genetics Home Reference, Gyrate Atrophy of the Choroid and Retina
Hereditary Ocular Diseases, Gyrate Atrophy
You may also wish to contact our Information Specialist:
Telephone: (301) 496-5248
The study NCT00001735 titled Gene Therapy for Gyrate Atrophy was never started. Therefore, no results are available.
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