16 items

Disruption of glucose transport to rods and cones shown to cause vision loss in retinitis pigmentosa

July 30, 2019

Retinitis pigmentosa (RP) is a common hereditary eye disorder that leads to the gradual deterioration of rod cells causing reduced peripheral vision and night vision. Subsequent loss of cone photoreceptors cause the loss of high-resolution daylight...

NEI Researchers Awarded Grants by the Knights Templar Eye Foundation

July 11, 2019

The Knights Templar Eye Foundation has awarded two NEI scientists grants to research inherited retinal degenerations, diseases that can cause blindness in early childhood.

Immune System Can Slow Degenerative Eye Disease, NIH-led Mouse Study Shows

June 17, 2019

A new study shows that the complement system, part of the innate immune system, plays a protective role to slow retinal degeneration in a mouse model of retinitis pigmentosa, an inherited eye disease.

Researchers find potential new gene therapy for blinding disease

August 20, 2018

Scientists funded by the National Eye Institute (NEI) report a novel gene therapy that halts vision loss in a canine model of a blinding condition called autosomal dominant retinitis pigmentosa (adRP).

Immune cells in the retina can spontaneously regenerate

March 21, 2018

Immune cells called microglia can completely repopulate themselves in the retina after being nearly eliminated, according to a new study in mice from scientists at the National Eye Institute (NEI).

Breast cancer drug dampens immune response, protecting light-sensing cells of the eye

March 13, 2017

The breast cancer drug tamoxifen appears to protect light-sensitive cells in the eye from degeneration, according to a new study in mice.

Five innovations harness new technologies for people with visual impairment, blindness

February 3, 2017

During Low Vision Awareness Month, the National Eye Institute (NEI), part of the National Institutes of Health, is highlighting new technologies and tools in the works to help the 4.1 million Americans living with low vision or blindness.

Retinitis Pigmentosa May Be Treated by Reprogramming Sugar Metabolism

November 14, 2016

NEI-funded researchers at Columbia University Medical Center have shown that vision loss associated with a form of retinitis pigmentosa can be slowed dramatically by reprogramming the metabolism of photoreceptors, or light sensors, in the retina.

CRISPR Used to Repair Blindness-causing Genetic Defect in Patient-derived Stem Cells

January 27, 2016

Columbia University Medical Center (CUMC) and University of Iowa scientists have used a new gene-editing technology called CRISPR to repair a genetic mutation responsible for retinitis pigmentosa (RP), an inherited condition

Gene Editing Technique Improves Vision in Rats with Inherited Blindness

January 7, 2016

A new technique that has the potential to treat inherited diseases by removing genetic defects has been shown for the first time to hinder retinitis pigmentosa, a degenerative eye disease with no known cure that can lead to blindness.