41 items

Nano-sized solution for efficient and versatile CRISPR gene editing

September 17, 2019

CRISPR gene-editing technology holds tremendous promise for treating or curing a wide range of devastating disorders, including vision loss.

NEI Researchers Awarded Grants by the Knights Templar Eye Foundation

July 11, 2019

The Knights Templar Eye Foundation has awarded two NEI scientists grants to research inherited retinal degenerations, diseases that can cause blindness in early childhood.

With Single Gene Insertion, Blind Mice Regain Sight

March 15, 2019

Researchers at the University of California, Berkeley, find that restoring opsins with gene therapy can make 'blind' cells light-sensitive; potential human treatment within three years.

Molecular Classification and Comparative Taxonomies of Foveal and Peripheral Cells in Primate Retina

February 21, 2019

A team of researchers led by Harvard's Joshua Sanes applied high-throughput genetic sequencing methods to create the first cellular atlas of the primate retina.

Nitisinone Increases Melanin in People With Albinism

February 20, 2019

A small pilot clinical study at the National Eye Institute (NEI) suggests that the drug nitisinone increases melanin production in some people with oculocutaneous albinism type 1B (OCA-1B), a rare genetic disease that causes pale skin and hair and poor vi

NIH Researchers Hone in on Genes Linked to Age-Related Macular Degeneration

February 11, 2019

National Eye Institute scientists led a collaborative study and zeroed in on genes associated with age-related macular degeneration (AMD), a leading cause of vision loss and blindness among people age 65 and older.

300 Blind Mice Uncover Genetic Causes of Eye Disease

December 21, 2018

Hundreds of new genes linked to blindness and other vision disorders have been identified in a screen of mouse strains. Many of these genes are likely important in human eye vision and the results could help identify new causes of hereditary blindness.

Researchers find potential new gene therapy for blinding disease

August 20, 2018

Scientists funded by the National Eye Institute (NEI) report a novel gene therapy that halts vision loss in a canine model of a blinding condition called autosomal dominant retinitis pigmentosa (adRP).

Gene regulator may contribute to protein pileup in exfoliation glaucoma

July 19, 2018

Scientists have evidence that variants of the same gene that enables us to make connective tissue by crosslinking proteins is associated with unusual glaucoma.

NEI funded researchers identify 133 genetic variants that predict glaucoma risk

May 31, 2018

Researchers funded by the National Eye Institute (NEI) have identified 133 genetic variants that predict with 75-percent accuracy a person’s risk for developing glaucoma related to elevated pressure within the eye.