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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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Female shown from overhead standing with her eye open receiving OCT scan.

NEI-funded technology promises to broaden access to retinal scanning

A National Eye Institute-funded project at Duke University has yielded a fully automated optical coherence tomography (OCT) device that does not require a trained operator and promises to broaden access to retinal imaging technology.
Eye is shown connected to visual processing regions of the brain via the optic nerve. Enlargement of retina shows photorecetors, biopolar cells and retinal ganglion cells.

Scientists discover gene therapy provides neuroprotection to prevent glaucoma vision loss

A form of gene therapy protects optic nerve cells and preserves vision in mouse models of glaucoma, according to research supported by NIH’s National Eye Institute. The findings suggest a way forward for developing neuroprotective therapies for glaucoma.
Two boys smile at camera. Dark spot in center of image represents vision loss from AMD.

HtrA1 augmentation is potential therapy for age-related macular degeneration

Research from the University of Utah explains why people with genetic variants may develop age-related macular degeneration (AMD) and identifies a potential therapeutic pathway for slowing disease progression.
Tiarnan Keenan

Patients use device to monitor AMD at home

Tiarnan Keenan, NEI Division of Epidemiology and Clinical Applications, and colleagues found that people with age-related macular degeneration (AMD) can successfully use the Notal Home OCT device to monitor their disease.
eye anatomy graphic

Melanoma of the eye: preclinical tests show path toward treatment

Researchers at UAB have discovered a small molecule inhibitor that dampens the potent drivers of uveal melanoma.
neurons

How neurons get past "no"

When looking at a complex landscape, the eye needs to focus in on important details without losing the big picture. Now, a new study by Salk scientists shows how inhibitory neurons play a critical role in this process.z
bacteria

E.U. - U.S. NIH collaborative symposium and workshop on AMD and the microbiome

NEI and European researchers hosted international investigators on June 18, 2021, to present and discuss recent advances in age-related macular degeneration (AMD) and its relationship to the microbiome.
Brain illustration with recycling logo

NIH-funded study shows children recycle brain regions when acquiring new skills

Scientists studied the brain activity of school-aged children during development and found that regions that activated upon seeing limbs (hands, legs, etc.) subsequently activated upon seeing faces or words when the children grew older.
Cells with red nuclei and long green processes

Scientists unravel the function of a sight-saving growth factor

Researchers at the National Eye Institute (NEI) have determined how certain short protein fragments, called peptides, can protect neuronal cells found in the light-sensing retina layer at the back of the eye.
Box of tissues

What makes us sneeze?

A team led by researchers at Washington University School of Medicine in St. Louis has identified, in mice, specific cells and proteins that control the sneeze reflex.

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