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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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Chirag Jhaveri, MD, examines the eyes of a patient.

A type of ‘step therapy’ is an effective strategy for diabetic eye disease

Clinical trial results from the DRCR Retina Network suggest that a specific step strategy gives results similar to starting off with the higher-priced drug.
NEI AGI audacious Goals Initiative for Regenerative Medicine

NEI's regenerative medicine initiative making progress toward its audacious goal

A new report outlines progress toward the National Eye Institute's Audacious Goals Initiative (AGI), an effort to restore vision through research in regenerative medicine. The report, published in Nature Medicine.
Colorful artistic visualization of the retina.

Measuring Levels of Proteins in Eye Fluid May Accurately Predict Need for Lifelong Macular Degeneration Therapy

Johns Hopkins Medicine researchers say they have found that levels of a specific protein appears to help accurately predict whether people with the wet form of age-related macular degeneration may need lifelong, frequent eye injections to preserve vision.
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New research examines vision screenings in older drivers

New research from the University of Alabama at Birmingham Marnix E. Heersink School of Medicine is shining a light on whether vision screenings for older drivers identify those who are likely to have motor vehicle collisions in the next few years.

NIH study confirms benefit of supplements for slowing age-related macular degeneration

The AREDS2 formula not only reduces risk of lung cancer due to beta-carotene, but is also more effective at reducing risk of AMD progression, compared to the original formula.
Comparison of two retinal images.

Gene therapy for rare eye disease safe but lacks efficacy in early trial

A 28-patient phase 1 gene therapy clinical trial for the degenerative retinal disease Leber hereditary optic neuropathy (LHON) found no significant safety concerns; however, treatment failed to improve or slow vision loss, with even the highest dose.

Retinal cell map could advance precise therapies for blinding diseases

Researchers have identified distinct differences among the cells comprising a tissue in the retina that is vital to human visual perception. The scientists from the National Eye Institute (NEI) discovered five subpopulations of retinal pigment epithelium.
Schematic shows blood vessel leakage on side of retina

Vision improvement is long-lasting with treatment for blinding blood vessel condition

NIH-funded study finds many patients with retinal vein occlusion have vision benefits, but require long-term monitoring and treatment
Photoreceptor degeneration tied to lipofuscin accumulation.

Advancing a treatment for a common eye disease that lacks one

The road from discovering a potential drug to getting the therapy into the hands of patients is a long and uncertain one. An NIH program called Blueprint Neurotherapeutics Network helps basic researchers prep for clinical trials and regulatory approval.
screen shot of a Zoom meeting

NEI hosts international strategic planning meeting

The digital summit of global partners in vision research discussed opportunities for collaboration.