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Home » Strategic Planning » NEI Workshop on Ocular Pain and Sensitivity » Summary of "white papers" by NEI Workshop on Ocular Pain and Sensitivity Participants

Summary of "white papers"
by NEI Workshop on Ocular Pain and Sensitivity Participants

September 30-October 1, 2010

White Papers

Prior to the meeting, each participant was asked to provide a "white paper" that summarized important recent research both in their own lab as well as by others in the field. Below, you will find a summary of the key points for discussion identified in the pre-workshop white papers.

Gaps, scientific opportunities, and unanswered questions

There are many types of ocular pain, including pain at the ocular surface, deep ocular or orbital pain, and referred pain. Different types of sensitivities may exist, including burning, itching, dry, or gritty sensations, or no sensation at all. The most common reason for discomfort at the ocular surface is categorized as dry eye.

Below, you will find a compilation of unanswered questions, gaps, and scientific opportunities identified in the pre-workshop white papers submitted by workshop participants. Several different themes arose, and they are summarized here:

Clinical Classification/Diagnosis

Functional innervation of the eye

Molecular and cellular mechanisms

Central mechanisms/sensitization

Role of inflammation

Prevention/ causes of pain

Treatment strategies



Department of Health and Human Services NIH, the National Institutes of Health USA.gov